Geranium (1,3-Dimethylamylamine or Methylhexamine)
This plant contains a powerful compound which has been shown to be more potent than ephedrine in some respects, but falls just short of being as powerful as amphetamine.
Like ephedrine, it produces sympathomimetic effects in the body.
Schizandrol A
This compound is an exciting one...
It has not only been shown to outperform amphetamine in cognitive tasks involving focus, but it has also been shown to greatly increase the capacity of muscles to perform work,while also increasing physical force. In essence, it is able to provide a stimulating effect to the body and mind [1].
Last, but certainly not least; unlike various stimulants which can increase catabolic hormone levels (i.e. glucocorticoids), this compound has been shown to lower levels of hormones like cortisol in animal models [2].
And, as we all know, cortisol is dramatically increased during a workout and can stop muscle growth in its tracks.
Schizandrol A will help keep cortisol at bay so you can get bigger, stronger & leaner!
Don't get confused with the cheap, ineffective Shizandra found in some other products. Our Schizandrol A is a potent Engineered Extract only found in USPlabs Jack3d.
Methylxanthines (Caffeine & Theophylline)
Both of these compounds belong to the family of methylxanthine compounds. They are both able to stimulate the CNS, while also stimulating contractility of skeletal muscle directly and this may partially be due to the release of catecholamines such as norepinephrine.
Caffeine also has the benefit of fighting fatigue and drowsiness; enhancing the flow of thoughts; increasing alertness and improving intellectual efforts along with producing euphoria or a sense of well-being in some cases. Just as these methylxanthines can increase the effectiveness of compounds such as ephedrine, it is thought that it may do the same for the unique compound found in Geranium [3-6].
In terms of specifics, at the cortical level, caffeine is also thought to promote increased wakefulness or vigilance, via adenosine receptor antagonism, causing stimulation of cholinergic neurons in the basal forebrain and reinforcing inhibition exerted upon sleep-promoting GABA neurons. The stimulant effects are exerted directly upon the cerebral cortex, medulla oblongata, and spinal cord.
In addition to these beneficial effects, we have included a precise combination of these methylxanthine compounds which allows for a longer, more powerful, and sustained effect.
This is because these compounds are a shared substrate for the same metabolic enzyme, thus, when the two are co-ingested, one compound is "sacrificed" while the other is "spared" resulting in decreased elimination of the active constituent [7].
The end result is that you no longer have to worry about feeling stimulated for an hour or two, followed by a quick crash...
With our precise combination, you get a long-lasting and sustained effect.
...Most formulas just throw in a ton of caffeine and hope for the best.
USPlabs Jack3d has a precise blend of compounds that will not only get you flying through your workouts like a mad man, but will allow you to have hours upon hours of energy without a harsh crash at the end.
Caffeine & theophylline are perfectly blended for a powerful synergistic effect.
This is one area where USPlabs Jack3d truly separates itself. It's not 300, 400 or 500 mgs of caffeine thrown in so you can "feel it." It's the proper stimulants in the proper dosages.
Beta-alanine
Beta-alanine serves as the rate-limiting precursor of carnosine and as such, it has been shown that by supplementing with beta-alanine, you can greatly increase carnosine levels in skeletal muscle tissue.
Carnosine is an extremely important dipeptide that is generally present in rather high concentrations in skeletal muscle, though it is also found in nervous tissue and other excitable tissues as well [12-16].
It is so important because it acts as a buffer of sorts, preventing the increase of acidity or Hydrogen ion accumulation in skeletal muscle; something which is thought to contribute to the fatiguing of muscles.
Furthermore, there is evidence that by increasing carnosine levels, power output can be increased as well. In short, you are able to improve your power output, while also delaying fatigue; you can lift more explosively and for longer periods.
It is no coincidence that the most explosive athletes (e.g. sprinters) in the world have higher carnosine levels in their muscles. Looking to the animals of our world provides us with yet another example; the most explosive animals such as greyhounds and thoroughbred horses also have the highest level of carnosine in their muscle tissue as well.
Creatine Monohydrate
While we may negate the increase in Hydrogen ion levels in skeletal muscle by increasing carnosine levels, we still must overcome one more obstacle in order to allow us to prevent fatigue while working out. In this case, we must use a compound which can ultimately increase the adenosine triphosphate (ATP) levels in muscle. ATP, as we all know, is a high energy nucleotide which acts as the major energy carrying molecule in our bodies.
Consequently, muscle fatigue is also related to energy loss in skeletal muscle, specifically, ATP being converted to adenosine diphosphate (ADP). In effect, one phosphate group is lost and must be replenished in order for the muscle cell to continue on working.
By supplementing with creatine, we are able to increase the levels of phosphocreatine in muscle. Phosphocreatine is a high energy buffering compound which is able to donate a phosphate group to ADP, allowing the formation of ATP once again.
In short, we can prevent or reduce fatigue from occurring by increasing phosphocreatine levels, which in turn will allow for the regeneration of ATP from ADP.
By addressing both the regeneration of ATP, while also limiting Hydrogen ion accumulation, we are able to provide a one-two combination that effectively reduces fatigue to an amazing degree.
If this weren't enough, the compound we have included may also increase the swelling of muscle cells, possibly increasing protein synthesis or inhibiting catabolism; the end result being an increase in muscle mass.
While creatine monohydrate isn't new or ground-breaking, it's scientifically sound, proven millions of times over in the real-world and an absolute must in any pre-workout formula.