Tribulus terrestris is a plant that grows in many tropical and moderate areas of the world. It is the steroidal saponins, particularly the dominant saponin protodioscin, that are responsible for the pharmacological activities of tribulus. Tribulus terrestris boosts testosterone levels by stimulating the increase of luteinizing hormone (LH). When LH levels are increased, the natural production of testosterone also increases.

Cucurbita pepo and saw palmetto extract are two resources to prevent testosterone from becoming "deactivated." The cucurbita pepo seeds’ principal constituent inhibits the conversion of testosterone into dihydrotesterone. As a natural source of zinc, cucurbita pepo also helps to optimize the production of testosterone. Saw palmetto berries consist of a volatile oil, which supplies phytosterols. These ingredients not only control the conversion of testosterone into DHT (DHT is formed when the male hormone testosterone interacts with the enzyme 5-alpha reductase), but also block its binding to the prostate cells. Saw palmetto also has anti-estrogenic and anti-androgenic effects.

When testosterone binds to SHBG (sex hormone-binding globulin), it loses its biological activity and becomes known as "bound testosterone," as opposed to the desirable "free testosterone." Nettle root extract provides a unique mechanism for increasing levels of free testosterone. Constituents of nettle root bind to SHBG in place of testosterone, thus reducing SHBG's binding of free testosterone. Nettle also inhibits the binding of DHT to attachment sites on the prostate membrane and inhibits enzymes, such as 5 alpha reductase that cause testosterone to convert into DHT. The combination of nettle root with avena sativa also leads to an increase of aerobic power and muscle strength.

Avena sativa is a botanical extract that has traditionally been used to increase strength, mind, spirit and body. It has also been found to free up testosterone that's stuck to other compounds in your body. Avena sativa is a recognized mood enhancer and has traditionally been used to help with recovery from exhaustion and low mood. It works well as an addition to tribulus, enhancing feelings of well being and restoring energy.

Researchers have observed that metabolism of estrogen occurs via one of two pathways: The ‘harmful’ metabolic pathway, 16 alpha-hydroxylation, or the ‘beneficial’ metabolic pathway, 2-hydroxylation. Indole-3-Carbinol (I3C) can shift the production of estrogen metabolites away from dangerous 16-hydroxy in favor of beneficial 2-hydroxy metabolites. Indole-3-carbinol is converted by stomach acid into diindolymethane (DIM) and indole (3,2,b) carbazole (ICZ). DIM produces more ‘good’ estrogen metabolites, which compete with testosterone for protein binding, and help maintain a higher free testosterone level. The ‘good’ estrogen metabolites. along with increased free testosterone promoted by DIM, increase fat mobilization and a fat-burning metabolism.

Another reason testosterone production can decline is because of oxidative damage directed at the tissues that synthesize testosterone. Antioxidants support testosterone production. This is where daidzein and alpha lipoic acid do their best work. Daidzein is an isoflavone. This compound, found only in plants, has antioxidant activity. Alpha lipoic acid also acts as an antioxidant, repairing a wide array of free radical damage at the cellular level, keeping cells healthy, and aiding in nutrient absorption. Alpha lipoic acid aids in the conversion of carbohydrates into energy, improves metabolism, and helps to maintain blood sugar.

The flavonoids in Hawthorne berry have the ability to dilate coronary blood vessels (the vessels supplying the heart with vital oxygen, blood, and nutrients) and promote the heart's pumping ability. Some of the flavonoids increase the force of contraction of the heart by inhibiting the enzyme cAMP phosphodiesterase (the enzyme responsible for breaking down cyclic adenosine monophosphate). Cyclic AMP is an intracellular secondary messenger of luteinizing hormone (LH).

TestostroGrow 2 HP is a versatile time-release anabolic stack that combines the most effective testosterone stimulators available. It has been precisely formulated to potentiate testosterone in order to ensure a steady state of increased testosterone for more successful anabolic results.